S.L. 439.20 Art. 4Principle of replacement, reduction and refinement.

(1) The competent authority shall ensure that, wherever possible, a scientifically satisfactory method or testing strategy, not entailing the use of live animals, shall be used instead of a procedure. USED FOR SCIENTIFIC PURPOSES

(2) The competent authority shall ensure that the number of animals used in projects is reduced to a minimum without compromising the objectives of the project.

(3) The competent authority shall ensure refinement of breeding, accommodation and care, and of methods used in procedures, eliminating or reducing to the minimum any possible pain, suffering, distress or lasting harm to the animals.

(4) This regulation shall, in the choice of methods, be implemented in accordance with regulation 13.